ChemicalBook > CAS DataBase List > 2-(ACETYLOXY)-4-[(NITROOXY)METHYL]PHENYL ESTER, BENZOIC ACID

2-(ACETYLOXY)-4-[(NITROOXY)METHYL]PHENYL ESTER, BENZOIC ACID

Product Name
2-(ACETYLOXY)-4-[(NITROOXY)METHYL]PHENYL ESTER, BENZOIC ACID
CAS No.
287118-97-2
Chemical Name
2-(ACETYLOXY)-4-[(NITROOXY)METHYL]PHENYL ESTER, BENZOIC ACID
Synonyms
NCX 4040;NO-Aspirin;NO-ASPIRIN 2;2-(Acetyloxy)benzoic acid 4-(nitroxymethyl)phenyl ester;2-(Acetyloxy)benzoic acid 4-[(nitrooxy)methyl]phenyl ester;2-(ACETYLOXY)-4-[(NITROOXY)METHYL]PHENYL ESTER, BENZOIC ACID;Benzoic acid, 2-(acetyloxy)-, 4-[(nitrooxy)methyl]phenyl ester
CBNumber
CB9343492
Molecular Formula
C16H13NO7
Formula Weight
331.28
MOL File
287118-97-2.mol
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2-(ACETYLOXY)-4-[(NITROOXY)METHYL]PHENYL ESTER, BENZOIC ACID Property

Melting point:
83-86°C
Boiling point:
495.7±40.0 °C(Predicted)
Density 
1.347±0.06 g/cm3(Predicted)
storage temp. 
-20°C
solubility 
DMSO: soluble15mg/mL (clear solution)
form 
powder
color 
white to beige
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Safety

Hazard Codes 
Xi
Risk Statements 
41-43
Safety Statements 
26-36/37-39
RIDADR 
UN 3077 9 / PGIII
WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H317May cause an allergic skin reaction

H318Causes serious eye damage

H400Very toxic to aquatic life

Precautionary statements

P273Avoid release to the environment.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
SML0414
Product name
NCX 4040
Purity
≥98% (HPLC)
Packaging
5mg
Price
$110
Updated
2024/03/01
Sigma-Aldrich
Product number
SML0414
Product name
NCX 4040
Purity
≥98% (HPLC)
Packaging
25mg
Price
$353
Updated
2024/03/01
Tocris
Product number
4531
Product name
NCX 4040
Purity
≥98%(HPLC)
Packaging
10
Price
$173
Updated
2021/12/16
Tocris
Product number
4531
Product name
NCX 4040
Purity
≥98%(HPLC)
Packaging
50
Price
$666
Updated
2021/12/16
TRC
Product number
N633005
Product name
NO-Aspirin
Packaging
250mg
Price
$1060
Updated
2021/12/16
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2-(ACETYLOXY)-4-[(NITROOXY)METHYL]PHENYL ESTER, BENZOIC ACID Chemical Properties,Usage,Production

Chemical Properties

Pale Yellow Solid

Uses

A novel nitric oxide-releasing aspirin,

Biochem/physiol Actions

NCX 4040 is a nitric oxide-donating form of aspirin. NCX 4040 inhibits cyclooxygenase activity and releases NO, which can down-regulate COX2 expression and reduce the levels of superoxide accumulation. In the human monocytic cell line THP1, the compound inhibits PGE2 production and cytokine expression, and appears to stabilize IkB by inhibiting proteasome function. NCX 4040 has been shown to induce apoptosis in several tumor cell lines.

2-(ACETYLOXY)-4-[(NITROOXY)METHYL]PHENYL ESTER, BENZOIC ACID Preparation Products And Raw materials

Raw materials

Preparation Products

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2-(ACETYLOXY)-4-[(NITROOXY)METHYL]PHENYL ESTER, BENZOIC ACID Suppliers

TargetMol Chemicals Inc.
Tel
+1-781-999-5354 +1-00000000000
Email
marketing@targetmol.com
Country
United States
ProdList
19892
Advantage
58

287118-97-2, 2-(ACETYLOXY)-4-[(NITROOXY)METHYL]PHENYL ESTER, BENZOIC ACIDRelated Search:


  • NO-ASPIRIN 2
  • NCX 4040
  • 2-(ACETYLOXY)-4-[(NITROOXY)METHYL]PHENYL ESTER, BENZOIC ACID
  • NO-Aspirin
  • 2-(Acetyloxy)benzoic acid 4-(nitroxymethyl)phenyl ester
  • 2-(Acetyloxy)benzoic acid 4-[(nitrooxy)methyl]phenyl ester
  • Benzoic acid, 2-(acetyloxy)-, 4-[(nitrooxy)methyl]phenyl ester
  • 287118-97-2
  • Aromatics
  • Inhibitors
  • Intermediates & Fine Chemicals
  • Nitric Oxide Reagents
  • Pharmaceuticals